STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AlgDCOG1004 Predicted UDP-glucose 6-dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (436 aa)    
Predicted Functional Partners:
RAM_02810
COG0438 Glycosyltransferase.
  
 0.969
gmd
GDPmannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
 
 
 0.950
RAM_05170
Mannose-1-phosphate guanylyltransferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).
  
 
 0.938
FruA
PTS system, fructose-specific IIBC component; COG1445 Phosphotransferase system fructose-specific component IIB.
     
 0.843
RAM_38105
Beta-mannosidase; COG2755 Lysophospholipase L1 and related esterases.
  
 
  0.816
xylA
COG2115 Xylose isomerase; Belongs to the xylose isomerase family.
     
 0.811
GutB
COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.
  
 
  0.809
ScrK
Fructokinase; COG0524 Sugar kinases, ribokinase family.
    
  0.804
RAM_09345
Oxidoreductase; COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).
   
 
  0.802
RAM_15725
Oxidoreductase; COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).
   
 
  0.802
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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