STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
RifECOG3321 Polyketide synthase modules and related proteins. (3413 aa)    
Predicted Functional Partners:
RifA
Rifamycin polyketide synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
0.987
RAM_27510
COG1020 Non-ribosomal peptide synthetase modules and related proteins.
 
 0.971
RAM_18765
Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
 
 0.968
RAM_18760
Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
 
 0.965
RAM_20005
Polyketide synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
0.930
RAM_27060
Hypothetical protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
 
 0.873
rifF
N-acetyltransferase/amide synthase; Catalyzes the release of the completed linear polyketide from the rif PKS by forming an intramolecular amide bond, in this way terminating polyketide assembly and forming the macrocyclic compound proansamycin X, an intermediate in the rifamycin B biosynthesis.
     
 0.866
RifB
COG3321 Polyketide synthase modules and related proteins.
 
 
0.857
RAM_31995
COG1020 Non-ribosomal peptide synthetase modules and related proteins.
 
 0.845
RfbB
COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
  
 0.843
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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