STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rifNKanosamine kinase; Involved in the biosynthesis of 3-amino-5-hydroxybenzoate (AHBA), a compound that then serves as the starter unit for the assembly of a polyketide during the biosynthesis of rifamycin B and other ansamycin antibiotics. Catalyzes only the phosphorylation of kanosamine to yield kanosamine 6-phosphate. (303 aa)    
Predicted Functional Partners:
RifM
COG0637 Predicted phosphatase/phosphohexomutase.
 
  
 0.987
rifL
Oxidoreductase RifL; In a complex with RifK, RifL may catalyze the oxidation of UDP-glucose to UDP-3-keto-D-glucose, which would then be used by RifK to produce UDP-kanosamine. Is not able to use dTDP-glucose as substrate.
 
   
 0.833
RAM_40225
COG1940 Transcriptional regulator/sugar kinase.
  
    0.776
RAM_19090
COG1940 Transcriptional regulator/sugar kinase.
  
     0.774
RAM_47640
COG1940 Transcriptional regulator/sugar kinase.
  
     0.774
RAM_17390
COG1940 Transcriptional regulator/sugar kinase.
  
     0.773
RAM_25795
COG1940 Transcriptional regulator/sugar kinase.
 
     0.773
RAM_15180
COG1940 Transcriptional regulator/sugar kinase.
  
     0.772
RAM_20255
Glucokinase; COG1940 Transcriptional regulator/sugar kinase.
  
     0.770
RAM_21945
COG1940 Transcriptional regulator/sugar kinase.
  
     0.769
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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