STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_03785COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). (359 aa)    
Predicted Functional Partners:
RAM_03790
ATP/GTP-binding protein; COG0802 Predicted ATPase or kinase.
       0.881
Alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
     
 0.868
nnrD
Ribokinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NA [...]
  
   0.686
xylB
D-xylulose kinase; COG1070 Sugar (pentulose and hexulose) kinases.
       0.657
RAM_03765
COG1349 Transcriptional regulators of sugar metabolism.
       0.654
RAM_03775
COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.
       0.654
RAM_02190
COG1396 Predicted transcriptional regulators.
  
     0.551
RAM_02410
COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase.
  
   0.520
RAM_41170
Hypothetical protein.
  
     0.519
GalE-2
UDP-glucose 4-epimerase; COG0451 Nucleoside-diphosphate-sugar epimerases.
  
   0.502
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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