STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_03810Peptidase M22, glycoprotease family protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. (220 aa)    
Predicted Functional Partners:
tsaD
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
 
 0.999
RAM_03790
ATP/GTP-binding protein; COG0802 Predicted ATPase or kinase.
 
 0.997
RimI
Ribosomal-protein-alanine N-acetyltransferase; COG0456 Acetyltransferases.
 
 
 0.968
RAM_03800
acetyl/propionyl-CoA carboxylase, carboxyltransferase subunit; COG0777 Acetyl-CoA carboxylase beta subunit.
  
    0.751
BirA
COG0340 Biotin-(acetyl-CoA carboxylase) ligase.
 
    0.697
pheT
phenylalanyl-tRNA synthetase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
    0.684
RAM_39985
SUA5/YciO/YrdC/YwlC family protein; COG0009 Putative translation factor (SUA5); Belongs to the SUA5 family.
 
  
 0.662
RAM_35300
COG0009 Putative translation factor (SUA5); Belongs to the SUA5 family.
 
  
 0.660
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.571
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
  
 0.570
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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