STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
RAM_04085COG0739 Membrane proteins related to metalloendopeptidases. (255 aa)    
Predicted Functional Partners:
RAM_45425
Penicillin binding protein; COG0744 Membrane carboxypeptidase (penicillin-binding protein).
  
   
 0.697
RAM_15390
Penicillin-binding protein; COG0744 Membrane carboxypeptidase (penicillin-binding protein).
  
   
 0.653
RAM_09250
Glycosyl transferase family 51; COG0744 Membrane carboxypeptidase (penicillin-binding protein).
  
   
 0.604
Pbp
Penicillin binding protein; COG0744 Membrane carboxypeptidase (penicillin-binding protein).
  
   
 0.589
MrcB
Penicillin binding protein; COG0744 Membrane carboxypeptidase (penicillin-binding protein).
  
   
 0.565
RAM_10340
Protease; COG0750 Predicted membrane-associated Zn-dependent proteases 1.
 
  
 0.533
FtsX
Cell division transport system permease protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
  
 0.518
dnaA
Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
  
  
 0.516
FtsW-2
COG0772 Bacterial cell division membrane protein; Belongs to the SEDS family.
 
  
 0.497
mltG
Aminodeoxychorismate lyase-like protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
 
  
 0.491
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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