STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_04220Hypothetical protein; COG0177 Predicted EndoIII-related endonuclease. (193 aa)    
Predicted Functional Partners:
Nfo
COG0648 Endonuclease IV.
 
 
 0.797
XthA
COG0708 Exonuclease III.
  
 0.689
XthA-2
COG0708 Exonuclease III.
  
 0.689
RAM_04225
AraC family transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins.
     
 0.597
coaE
dephospho-CoA kinase/protein folding accessory domain-containing protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
  
  
 0.592
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.592
RAM_24810
COG0258 5'-3' exonuclease (including N-terminal domain of PolI).
 
 
 0.578
RAM_35865
Hypothetical protein; COG1796 DNA polymerase IV (family X).
 
   
 0.573
RAM_01260
Hypothetical protein.
  
     0.554
ligC-2
COG1793 ATP-dependent DNA ligase.
 
   
 0.550
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.