STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DacCCOG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (414 aa)    
Predicted Functional Partners:
FtsI
COG0768 Cell division protein FtsI/penicillin-binding protein 2.
 
 
 0.961
RAM_00265
Peptidoglycan glycosyl transferase; COG0768 Cell division protein FtsI/penicillin-binding protein 2.
 
 
 0.942
DacB
COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4).
     
 0.933
DacC-2
COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
  
  
 
0.928
RAM_04320
Integral membrane protein.
       0.607
AmiA-2
N-acetylmuramoyl-L-alanine amidase; COG3409 Putative peptidoglycan-binding domain-containing protein.
 
  
 0.529
RAM_47930
Glycoprotein.
  
    0.435
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
  
 0.434
RAM_27105
Hypothetical protein.
 
     0.425
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
 
  
 0.424
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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