STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_04555(S)-2-hydroxy-acid oxidase; COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. (356 aa)    
Predicted Functional Partners:
RAM_04560
COG2124 Cytochrome P450.
 
    0.820
RAM_04565
Cation:proton antiporter; COG0475 Kef-type K+ transport systems, membrane components.
       0.787
RAM_04550
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG0492 Thioredoxin reductase.
  
    0.785
RAM_04545
COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).
  
 
 0.628
RAM_44350
Lactate transporter LctP family protein; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
 
  
 0.593
RAM_04570
COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
       0.584
RAM_04575
COG0642 Signal transduction histidine kinase.
       0.584
RAM_10720
Lactate transporter LctP family protein; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
 
  
 0.584
RAM_36555
Hypothetical protein.
  
  
 0.554
RAM_04540
COG0789 Predicted transcriptional regulators.
       0.547
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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