STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MmsBCOG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases. (278 aa)    
Predicted Functional Partners:
RAM_04875
Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
  
    0.775
MmsB-2
COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
  
     0.760
MmsB-3
COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
  
     0.759
RAM_36860
6-phosphogluconate dehydrogenase-related protein; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
  
     0.758
RAM_04865
COG1733 Predicted transcriptional regulators.
       0.553
RAM_04880
COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.
       0.476
Gip
COG3622 Hydroxypyruvate isomerase; Belongs to the hyi family.
 
  
 0.453
RAM_04885
Hypothetical protein; COG1305 Transglutaminase-like enzymes, putative cysteine proteases.
       0.438
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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