STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BirACOG0340 Biotin-(acetyl-CoA carboxylase) ligase. (263 aa)    
Predicted Functional Partners:
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 
 0.966
RAM_21220
COG0439 Biotin carboxylase.
 
 
 0.913
Pyc
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
 
 
 0.885
RAM_03800
acetyl/propionyl-CoA carboxylase, carboxyltransferase subunit; COG0777 Acetyl-CoA carboxylase beta subunit.
 
   
 0.853
RAM_13395
UreA amidolyase; COG0439 Biotin carboxylase.
 
  
 0.846
RAM_14680
acyl-CoA carboxylase alpha chain; COG0439 Biotin carboxylase.
 
  
 0.845
RAM_40715
Acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein; COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit.
 
  
 0.845
RAM_04760
Acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein; COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit.
 
  
 0.844
RAM_13390
UreA amidolyase; COG0439 Biotin carboxylase.
 
  
 0.706
RAM_03810
Peptidase M22, glycoprotease family protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone.
 
    0.697
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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