STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_05195NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. (181 aa)    
Predicted Functional Partners:
RAM_05200
F420-0--gamma-glutamyl ligase.
      0.931
CofD
LPPG:FO 2-phospho-L-lactate transferase.
       0.880
nnrD
Ribokinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NA [...]
  
 0.834
RAM_05210
GCN5-related N-acetyltransferase; COG0006 Xaa-Pro aminopeptidase.
  
    0.790
RAM_05185
COG1725 Predicted transcriptional regulators.
       0.718
RAM_05190
Hypothetical protein.
       0.691
RAM_05180
Hypothetical protein.
       0.689
RAM_05215
Hypothetical protein.
       0.569
RAM_05630
COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.
  
 0.493
RAM_07850
COG0513 Superfamily II DNA and RNA helicases.
  
 0.493
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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