STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_05200F420-0--gamma-glutamyl ligase. (448 aa)    
Predicted Functional Partners:
CofD
LPPG:FO 2-phospho-L-lactate transferase.
 
 
 0.999
fbiD
Hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
 
   
 0.944
RAM_05195
NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.
      0.931
fbiC-3
FO synthase; COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes.
 
   
 0.822
fbiC
FO synthase; COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes.
 
   
 0.811
RAM_05210
GCN5-related N-acetyltransferase; COG0006 Xaa-Pro aminopeptidase.
       0.789
RAM_42925
Hypothetical protein.
 
   
 0.772
RAM_14790
Hypothetical protein.
 
   
 0.768
RAM_15125
Oxidoreductase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.
 
  
 0.765
RAM_05185
COG1725 Predicted transcriptional regulators.
 
     0.756
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.