STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_05455COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain). (425 aa)    
Predicted Functional Partners:
RAM_05450
COG4420 Predicted membrane protein.
 
     0.959
Mrp
ATP-binding protein involved in chromosome partitioning; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
     
 0.838
RAM_05460
Aminoglycoside O-phosphotransferase; COG3570 Streptomycin 6-kinase.
       0.782
RAM_05465
COG0330 Membrane protease subunits, stomatin/prohibitin homologs.
     
 0.566
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.496
RAM_13260
Hypothetical protein.
  
     0.474
secF
Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
  
 
 0.440
TrkA-2
Trk system potassium uptake protein TrkA; COG0569 K+ transport systems, NAD-binding component.
 
   
 0.431
RAM_45500
Hypothetical protein.
 
     0.418
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.