STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_05465COG0330 Membrane protease subunits, stomatin/prohibitin homologs. (293 aa)    
Predicted Functional Partners:
RAM_23765
Band 7 domain-containing protein; COG0330 Membrane protease subunits, stomatin/prohibitin homologs.
  
     0.771
RAM_27170
Peptidase M41; COG0465 ATP-dependent Zn proteases.
 
 0.760
ftsH
Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
 0.730
RAM_23760
COG1585 Membrane protein implicated in regulation of membrane protease activity.
 
  
 0.643
Mrp
ATP-binding protein involved in chromosome partitioning; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
  
   0.599
RAM_05455
COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain).
     
 0.571
RAM_05460
Aminoglycoside O-phosphotransferase; COG3570 Streptomycin 6-kinase.
       0.558
RAM_05450
COG4420 Predicted membrane protein.
       0.551
RAM_47855
Hypothetical protein; COG1678 Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family.
  
    0.528
arc
COG0464 ATPases of the AAA+ class.
   
 
 0.522
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.