| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CysG | HemD-2 | RAM_25450 | RAM_05720 | uroporphyrin-III C-methyltransferase/precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase; COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | COG1587 Uroporphyrinogen-III synthase. | 0.977 |
| CysG | HemD-3 | RAM_25450 | RAM_05745 | uroporphyrin-III C-methyltransferase/precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase; COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | COG1587 Uroporphyrinogen-III synthase. | 0.965 |
| CysG | MoaB | RAM_25450 | RAM_43735 | uroporphyrin-III C-methyltransferase/precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase; COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | Molybdenum cofactor biosynthesis protein B; COG0521 Molybdopterin biosynthesis enzymes. | 0.772 |
| CysG | NasB | RAM_25450 | RAM_05710 | uroporphyrin-III C-methyltransferase/precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase; COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | Nitrite reductase (NAD(P)H) large subunit; COG1251 NAD(P)H-nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.701 |
| CysG | NasC | RAM_25450 | RAM_05700 | uroporphyrin-III C-methyltransferase/precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase; COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | Electron transfer subunit of assimilatory nitrate reductase; COG1251 NAD(P)H-nitrite reductase. | 0.587 |
| CysG | NasD | RAM_25450 | RAM_05715 | uroporphyrin-III C-methyltransferase/precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase; COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases. | 0.745 |
| CysG | NasK | RAM_25450 | RAM_05705 | uroporphyrin-III C-methyltransferase/precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase; COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | COG2223 Nitrate/nitrite transporter. | 0.689 |
| CysG | moaC | RAM_25450 | RAM_43740 | uroporphyrin-III C-methyltransferase/precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase; COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | 0.531 |
| HemD-2 | CysG | RAM_05720 | RAM_25450 | COG1587 Uroporphyrinogen-III synthase. | uroporphyrin-III C-methyltransferase/precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase; COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | 0.977 |
| HemD-2 | HemD-3 | RAM_05720 | RAM_05745 | COG1587 Uroporphyrinogen-III synthase. | COG1587 Uroporphyrinogen-III synthase. | 0.907 |
| HemD-2 | MoaB | RAM_05720 | RAM_43735 | COG1587 Uroporphyrinogen-III synthase. | Molybdenum cofactor biosynthesis protein B; COG0521 Molybdopterin biosynthesis enzymes. | 0.461 |
| HemD-2 | NasA | RAM_05720 | RAM_05695 | COG1587 Uroporphyrinogen-III synthase. | Nitrate reductase catalytic subunit; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.929 |
| HemD-2 | NasB | RAM_05720 | RAM_05710 | COG1587 Uroporphyrinogen-III synthase. | Nitrite reductase (NAD(P)H) large subunit; COG1251 NAD(P)H-nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.961 |
| HemD-2 | NasC | RAM_05720 | RAM_05700 | COG1587 Uroporphyrinogen-III synthase. | Electron transfer subunit of assimilatory nitrate reductase; COG1251 NAD(P)H-nitrite reductase. | 0.934 |
| HemD-2 | NasD | RAM_05720 | RAM_05715 | COG1587 Uroporphyrinogen-III synthase. | COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases. | 0.957 |
| HemD-2 | NasK | RAM_05720 | RAM_05705 | COG1587 Uroporphyrinogen-III synthase. | COG2223 Nitrate/nitrite transporter. | 0.971 |
| HemD-3 | CysG | RAM_05745 | RAM_25450 | COG1587 Uroporphyrinogen-III synthase. | uroporphyrin-III C-methyltransferase/precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase; COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | 0.965 |
| HemD-3 | HemD-2 | RAM_05745 | RAM_05720 | COG1587 Uroporphyrinogen-III synthase. | COG1587 Uroporphyrinogen-III synthase. | 0.907 |
| HemD-3 | MoaB | RAM_05745 | RAM_43735 | COG1587 Uroporphyrinogen-III synthase. | Molybdenum cofactor biosynthesis protein B; COG0521 Molybdopterin biosynthesis enzymes. | 0.402 |
| HemD-3 | NasA | RAM_05745 | RAM_05695 | COG1587 Uroporphyrinogen-III synthase. | Nitrate reductase catalytic subunit; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.712 |