STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_05805Lipoprotein; COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain). (430 aa)    
Predicted Functional Partners:
RAM_05795
Hypothetical protein.
 
  
 0.961
MoxR
COG0714 MoxR-like ATPases.
 
  
 0.950
RAM_05790
Hypothetical protein.
 
  
 0.942
RAM_05785
Integral membrane protein.
 
     0.934
RAM_05810
COG1300 Uncharacterized membrane protein.
 
  
 0.843
RAM_05815
RDD domain-containing protein; COG1714 Predicted membrane protein/domain.
 
    0.791
nnrD
Ribokinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NA [...]
     
 0.645
purD
COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family.
      
 0.630
MoxR-3
COG0714 MoxR-like ATPases.
 
  
 0.572
RAM_40990
COG3571 Predicted hydrolase of the alpha/beta-hydrolase fold.
   
    0.552
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.