STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cobDAdenosylcobinamide-phosphate synthase CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (296 aa)    
Predicted Functional Partners:
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
 
 0.987
CobP
Adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase.
 
 
 0.983
CobO
cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase; COG2109 ATP:corrinoid adenosyltransferase.
 
  
 0.980
CobI
COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family.
 
  
 0.916
RAM_39920
Diol dehydratase; Belongs to the Cob(I)alamin adenosyltransferase family.
    
 0.913
CobL
precorrin-6Y C5,15-methyltransferase/precorrin-8W decarboxylase; COG2241 Precorrin-6B methylase 1.
 
  
 0.911
cobD-2
Adenosylcobinamide-phosphate synthase CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
  
  
 
0.909
cobB-2
Hydrogenobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
  
 0.879
CobH
precorrin-8X methylmutase; COG2082 Precorrin isomerase.
 
  
 0.878
CobM
COG2875 Precorrin-4 methylase; Belongs to the precorrin methyltransferase family.
 
  
 0.835
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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