STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HcaD-2Ferredoxin reductase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. (411 aa)    
Predicted Functional Partners:
RAM_05995
COG1141 Ferredoxin.
 
     0.843
RAM_05990
Hypothetical protein.
       0.768
RAM_32810
Alkane 1-monooxygenase; COG1773 Rubredoxin.
 
 
 0.623
NasD
COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.
 
  
 0.500
CysG
uroporphyrin-III C-methyltransferase/precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase; COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain).
  
  
 0.487
HemD
uroporphyrin-III C-methyltransferase HemD; COG0007 Uroporphyrinogen-III methylase.
  
  
 0.463
RAM_05980
Hypothetical protein.
       0.452
RpoE-11
RNA polymerase sigma-70 factor, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.
       0.452
RAM_05975
LuxR family transcriptional regulator fused with ATPase domain; COG3899 Predicted ATPase.
  
    0.443
PoxL
Pyruvate oxidase; COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases; Belongs to the TPP enzyme family.
  
  
 0.423
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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