STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TrxBThioredoxin reductase; COG0784 FOG: CheY-like receiver. (550 aa)    
Predicted Functional Partners:
RAM_07475
Two-component system sensor kinase; COG0642 Signal transduction histidine kinase.
 
 
 0.991
RAM_23045
Two-component system sensor kinase; COG2770 FOG: HAMP domain.
  
 
 0.976
RAM_34820
Two-component system sensor kinase; COG2770 FOG: HAMP domain.
  
 
 0.961
RAM_20890
Fused protein kinase and phosphatase containing multi-sensor domain; COG2202 FOG: PAS/PAC domain.
  
 
 0.947
RAM_01960
Signal transduction protein containing EAL, PAS and GGDEF domain; COG2202 FOG: PAS/PAC domain.
  
 
 0.933
RAM_30220
Two-component system sensor kinase; COG2202 FOG: PAS/PAC domain.
 
 
 0.913
MetB-2
COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
  
 
 0.913
TrxB-4
COG0492 Thioredoxin reductase.
 
  
0.910
IscS-2
Aminotransferase class V/cysteine desulfurase; COG0520 Selenocysteine lyase.
  
 
 0.909
SufS
Cysteine desulfurase/selenocysteine lyase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
  
 
 0.909
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.