STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_07610NAD binding oxidoreductase; COG0673 Predicted dehydrogenases and related proteins. (327 aa)    
Predicted Functional Partners:
IolD
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COG3962 Acetolactate synthase; Belongs to the TPP enzyme family.
 
  
 0.588
RAM_07615
ABC transporter substrate-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.
       0.545
RAM_07620
COG0765 ABC-type amino acid transport system, permease component.
       0.545
RAM_07625
COG1126 ABC-type polar amino acid transport system, ATPase component.
       0.545
RAM_07630
Aminotransferase class V; COG0520 Selenocysteine lyase.
       0.545
rifL
Oxidoreductase RifL; In a complex with RifK, RifL may catalyze the oxidation of UDP-glucose to UDP-3-keto-D-glucose, which would then be used by RifK to produce UDP-kanosamine. Is not able to use dTDP-glucose as substrate.
  
     0.505
GalK
COG0153 Galactokinase; Belongs to the GHMP kinase family. GalK subfamily.
 
 
 0.474
IolB
5-deoxy-glucuronate isomerase; COG3718 Uncharacterized enzyme involved in inositol metabolism.
  
  
 0.469
IolE-2
Inosose dehydratase; COG1082 Sugar phosphate isomerases/epimerases.
 
  
 0.465
IolE
Inosose dehydratase; COG1082 Sugar phosphate isomerases/epimerases.
 
  
 0.455
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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