STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_07650COG1131 ABC-type multidrug transport system, ATPase component. (299 aa)    
Predicted Functional Partners:
RAM_07655
COG0842 ABC-type multidrug transport system, permease component.
 
  
 0.960
RAM_33875
COG0842 ABC-type multidrug transport system, permease component.
 
  
 0.829
DesR-2
COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
 
    0.641
DesK
COG4585 Signal transduction histidine kinase.
 
    0.552
DesR
COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
 
    0.535
DesK-2
COG4585 Signal transduction histidine kinase.
 
    0.532
RAM_15400
COG1131 ABC-type multidrug transport system, ATPase component.
 
    
0.507
dinB
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
     
 0.487
RAM_07660
Hypothetical protein.
       0.484
RAM_07665
COG1846 Transcriptional regulators.
       0.484
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.