STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_07650COG1131 ABC-type multidrug transport system, ATPase component. (299 aa)    
Predicted Functional Partners:
RAM_07655
COG0842 ABC-type multidrug transport system, permease component.
 
  
 0.961
RAM_33875
COG0842 ABC-type multidrug transport system, permease component.
 
  
 0.832
DesR-2
COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
  
    0.642
DesK
COG4585 Signal transduction histidine kinase.
 
     0.542
DesR
COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
  
    0.536
DesK-2
COG4585 Signal transduction histidine kinase.
 
     0.521
RAM_15400
COG1131 ABC-type multidrug transport system, ATPase component.
 
    
0.506
dinB
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
    0.485
RAM_07660
Hypothetical protein.
       0.484
RAM_07665
COG1846 Transcriptional regulators.
       0.484
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.