STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PhoDCOG3540 Phosphodiesterase/alkaline phosphatase D. (523 aa)    
Predicted Functional Partners:
FolB
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
     
 0.970
folE
COG0302 GTP cyclohydrolase I.
    
 0.949
folE-2
COG0302 GTP cyclohydrolase I.
    
 0.949
PhoA-2
COG1785 Alkaline phosphatase; Belongs to the alkaline phosphatase family.
  
 
 0.946
PhoD-2
COG3540 Phosphodiesterase/alkaline phosphatase D.
  
  
 
0.927
RAM_34460
COG0285 Folylpolyglutamate synthase.
     
 0.713
RAM_07760
Hypothetical protein.
       0.668
FolP-5
COG0294 Dihydropteroate synthase and related enzymes.
     
 0.587
GlpQ-2
COG0584 Glycerophosphoryl diester phosphodiesterase.
 
  
 0.542
RAM_47580
Phosphatase; COG3211 Predicted phosphatase.
 
  
 0.471
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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