STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_07865Hydratase/decarboxylase; COG3971 2-keto-4-pentenoate hydratase. (257 aa)    
Predicted Functional Partners:
MhpF
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
  
 0.925
MhpE
4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
  
 0.876
Acd
COG1960 Acyl-CoA dehydrogenases.
     
 0.779
RAM_07860
Hypothetical protein.
       0.773
RAM_07870
Hypothetical protein.
       0.773
RAM_36900
Metapyrocatechase (catechol 2,3-dioxygenase); COG0346 Lactoylglutathione lyase and related lyases.
 
   
 0.692
mhpB
3-(2,3-dihydroxyphenyl)propionate dioxygenase.
 
  
 0.491
RAM_07850
COG0513 Superfamily II DNA and RNA helicases.
       0.465
RAM_37575
Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases.
  
     0.463
RAM_36890
3-oxosteroid 1-dehydrogenase; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
 
   
 0.411
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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