STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Coexpression
Experiments
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[Homology]
Score
ArgK-2LAO/AO transport system kinase; COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family. (321 aa)    
Predicted Functional Partners:
RAM_04660
COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit.
 0.998
RAM_04655
COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit.
 
 0.989
RAM_39870
COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit.
 
 0.989
icmF
methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
 
 
0.948
ArgK
Membrane ATPase/protein kinase; COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family.
  
  
 
0.917
Mce
methylmalonyl-CoA epimerase; COG0346 Lactoylglutathione lyase and related lyases.
 
  
 0.897
AtoB
Putative acyltransferase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
       0.784
RAM_04820
COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta).
 
   
 0.686
RAM_17130
COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta).
 
   
 0.675
RAM_35195
COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta).
 
   
 0.674
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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