STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MarR-2COG1846 Transcriptional regulators. (166 aa)    
Predicted Functional Partners:
RAM_14595
COG1316 Transcriptional regulator.
   
    0.707
RAM_08125
Hypothetical protein.
       0.681
RAM_29585
ATPase; COG3903 Predicted ATPase.
  
    0.664
RAM_14375
COG2345 Predicted transcriptional regulator.
   
    0.641
Acs-2
COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
     0.597
RAM_24120
COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.
   
    0.594
RAM_26895
COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.
   
    0.594
cobB
SIR2 family NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily.
   
    0.560
RAM_30450
COG0846 NAD-dependent protein deacetylases, SIR2 family.
   
    0.560
RAM_44685
COG0846 NAD-dependent protein deacetylases, SIR2 family.
   
    0.560
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.