STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_08135COG3118 Thioredoxin domain-containing protein. (323 aa)    
Predicted Functional Partners:
TrxB
Thioredoxin reductase; COG0784 FOG: CheY-like receiver.
  
 
 0.804
TrxB-3
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG0492 Thioredoxin reductase.
  
 
 0.702
TrxB-4
COG0492 Thioredoxin reductase.
  
 
 0.702
RAM_25330
Hypothetical protein.
  
    0.632
HemD
uroporphyrin-III C-methyltransferase HemD; COG0007 Uroporphyrinogen-III methylase.
  
  
 0.630
TrxB-2
COG0492 Thioredoxin reductase.
  
 
 0.561
RAM_08130
Hypothetical protein.
       0.552
GapA
COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.538
RAM_16890
COG0640 Predicted transcriptional regulators; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 
 0.521
atpA
F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
  
 
 0.516
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.