STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_08610Subtilisin family peptidase; COG1404 Subtilisin-like serine proteases; Belongs to the peptidase S8 family. (1125 aa)    
Predicted Functional Partners:
RAM_07075
COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.
  
    0.560
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
     
 0.480
RAM_47910
Hypothetical protein.
  
    0.478
RAM_25420
Hypothetical protein.
  
     0.475
RAM_05370
Hypothetical protein.
  
     0.472
RAM_37485
Rhs family protein; COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing proteins.
  
 
 0.471
RAM_13455
Hypothetical protein.
  
    0.462
SerA-2
COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.443
RAM_31305
COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases.
  
  
 0.439
RAM_46310
Hypothetical protein.
 
  
 0.422
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.