STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_09255Peptidoglycan glycosyl transferase; COG0744 Membrane carboxypeptidase (penicillin-binding protein). (130 aa)    
Predicted Functional Partners:
FtsI
COG0768 Cell division protein FtsI/penicillin-binding protein 2.
   
 0.683
RAM_00265
Peptidoglycan glycosyl transferase; COG0768 Cell division protein FtsI/penicillin-binding protein 2.
   
 0.682
RAM_09250
Glycosyl transferase family 51; COG0744 Membrane carboxypeptidase (penicillin-binding protein).
 
     0.609
DacB
COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4).
     
 0.595
htpX
COG0501 Zn-dependent protease with chaperone function; Belongs to the peptidase M48B family.
  
    0.520
RAM_09100
COG3599 Cell division initiation protein.
 
 
 
 0.506
RAM_15050
COG3599 Cell division initiation protein.
   
 
 0.494
RAM_15075
Penicillin-binding protein, transpeptidase; COG0768 Cell division protein FtsI/penicillin-binding protein 2.
 
 
 
 0.448
DnaN-2
COG0592 DNA polymerase sliding clamp subunit (PCNA homolog).
 
  
 0.407
topA
DNA topoisomerase I subunit omega; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus rem [...]
 
   
 0.401
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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