STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_09390COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (314 aa)    
Predicted Functional Partners:
GlxK
COG1929 Glycerate kinase; Belongs to the glycerate kinase type-1 family.
    
 0.979
kgd
Alpha-ketoglutarate decarboxylase; COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes.
  
 
 0.926
CitE-2
COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.925
GlcD
Oxidoreductase; COG0277 FAD/FMN-containing dehydrogenases.
 
 
 0.925
Dld
Glycolate oxidase; COG0277 FAD/FMN-containing dehydrogenases.
 
 
 0.924
GarR-2
2-hydroxy-3-oxopropionate reductase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
 
  
 0.917
AceB
COG2225 Malate synthase; Belongs to the malate synthase family.
  
 
 0.915
AceB-2
COG2225 Malate synthase; Belongs to the malate synthase family.
  
 
 0.915
GlxK-2
COG1929 Glycerate kinase; Belongs to the glycerate kinase type-1 family.
    
 0.914
Gip
COG3622 Hydroxypyruvate isomerase; Belongs to the hyi family.
  
 
 0.912
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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