STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LacI-2COG1609 Transcriptional regulators. (340 aa)    
Predicted Functional Partners:
RAM_09570
Sugar ABC transporter permease; COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.
 
  
 0.622
RAM_09575
COG1879 ABC-type sugar transport system, periplasmic component.
 
  
 0.620
RAM_09565
COG1129 ABC-type sugar transport system, ATPase component.
 
  
 0.615
IolE
Inosose dehydratase; COG1082 Sugar phosphate isomerases/epimerases.
 
    0.611
IolC
5-dehydro-2-deoxygluconokinase; COG0524 Sugar kinases, ribokinase family.
 
  
 0.606
RAM_09555
Hypothetical protein.
 
   
 0.559
IolG
Myo-inositol 2-dehydrogenase; COG0673 Predicted dehydrogenases and related proteins.
       0.545
IolB
5-deoxy-glucuronate isomerase; COG3718 Uncharacterized enzyme involved in inositol metabolism.
  
    0.506
IolD
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COG3962 Acetolactate synthase; Belongs to the TPP enzyme family.
       0.430
GltB
Glutamate synthase (NADPH/NADH) large chain; COG0067 Glutamate synthase domain 1.
    
 
 0.412
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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