STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Coexpression
Experiments
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[Homology]
Score
KdpECOG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (232 aa)    
Predicted Functional Partners:
KdpD
Two-component system sensor kinase; COG2205 Osmosensitive K+ channel histidine kinase.
 
 0.997
kdpC
K+-transporting ATPase ATPase C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
 
   
 0.946
kdpA
Potassium-transporting ATPase subunit A; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.
 
   
 0.945
kdpB
K+-transporting ATPase ATPase B chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
 
   
 0.941
RAM_44390
COG0642 Signal transduction histidine kinase.
 
   0.786
RAM_44320
Two-component system sensor kinase; COG0642 Signal transduction histidine kinase.
 
   0.785
RAM_25855
COG0642 Signal transduction histidine kinase.
 
   0.780
RAM_04575
COG0642 Signal transduction histidine kinase.
 
 
 0.769
SenX
COG0642 Signal transduction histidine kinase.
 
 
 0.768
RAM_40815
COG0642 Signal transduction histidine kinase.
 
   0.760
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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