STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_09875GGDEF domain-containing diguanylate cyclase; COG2199 FOG: GGDEF domain. (434 aa)    
Predicted Functional Partners:
RAM_42515
Signal transduction protein; COG2202 FOG: PAS/PAC domain.
 
 
 0.852
RAM_02995
Signal sensor protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
  
 0.837
RAM_20890
Fused protein kinase and phosphatase containing multi-sensor domain; COG2202 FOG: PAS/PAC domain.
  
 
 0.769
RAM_14510
Hypothetical protein; COG2200 FOG: EAL domain.
 
  
 0.757
RAM_01960
Signal transduction protein containing EAL, PAS and GGDEF domain; COG2202 FOG: PAS/PAC domain.
 
0.626
RAM_14610
Diguanylate cyclase/phosphodiesterase; COG2199 FOG: GGDEF domain.
 
 
0.581
RAM_30220
Two-component system sensor kinase; COG2202 FOG: PAS/PAC domain.
  
 
 0.550
RAM_09870
COG1309 Transcriptional regulator.
   
   0.535
RAM_10000
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
     0.513
RAM_09860
FAD-dependent oxidoreductase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.
       0.511
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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