STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xerCIntegrase/recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (302 aa)    
Predicted Functional Partners:
FtsK-5
COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins.
 
   
 0.755
RAM_41055
Hypothetical protein.
   
    0.748
RAM_10000
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
     
 0.717
FtsW-2
COG0772 Bacterial cell division membrane protein; Belongs to the SEDS family.
 
  
 0.680
RAM_01570
COG0287 Prephenate dehydrogenase.
  
    0.674
whiA
Putative sporulation transcription regulator whiA; Involved in cell division and chromosome segregation.
  
    0.672
RAM_40995
Hypothetical protein; Belongs to the SOS response-associated peptidase family.
   
    0.665
Smf
DNA processing protein; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake.
 
   
 0.620
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
  
 0.609
Apt
COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins.
   
  
 0.609
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.