STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_10380Penicillin-binding protein, transpeptidase; COG0768 Cell division protein FtsI/penicillin-binding protein 2. (586 aa)    
Predicted Functional Partners:
FtsW-2
COG0772 Bacterial cell division membrane protein; Belongs to the SEDS family.
 
 
 0.812
FtsQ
Cell division protein FtsQ; Essential cell division protein.
  
 
 0.794
RAM_45425
Penicillin binding protein; COG0744 Membrane carboxypeptidase (penicillin-binding protein).
 
 
 
 0.779
FtsW
COG0772 Bacterial cell division membrane protein; Belongs to the SEDS family.
 
 0.766
map-2
Methionyl aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
     
 0.739
RAM_15390
Penicillin-binding protein; COG0744 Membrane carboxypeptidase (penicillin-binding protein).
 
 
 
 0.732
RAM_10375
Acetyltransferase; COG3393 Predicted acetyltransferase.
 
     0.633
RAM_09250
Glycosyl transferase family 51; COG0744 Membrane carboxypeptidase (penicillin-binding protein).
 
 
 
 0.611
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
  
 0.587
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
 
 0.574
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.