STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YaeR-2Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases. (145 aa)    
Predicted Functional Partners:
RAM_10695
Hypothetical protein; COG2508 Regulator of polyketide synthase expression.
       0.553
RAM_19000
Riboflavin biosynthesis protein RibD.
 
    0.550
RAM_38285
Deaminase-reductase domain-containing protein; COG0262 Dihydrofolate reductase.
 
    0.539
RAM_02110
Riboflavin biosynthesis protein RibD; COG0262 Dihydrofolate reductase.
 
    0.536
fabH-2
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
   
   0.489
RAM_04910
Deaminase-reductase domain-containing protein; COG0262 Dihydrofolate reductase.
 
    0.473
RAM_26165
Riboflavin biosynthesis protein; COG0262 Dihydrofolate reductase.
 
    0.465
RAM_20320
Hypothetical protein; COG0262 Dihydrofolate reductase.
 
    0.462
RAM_06605
Hypothetical protein; COG0262 Dihydrofolate reductase.
 
    0.458
nuoI
NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
  
 0.453
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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