STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_11145Iron-sulfur cluster biosynthesis protein; Belongs to the HesB/IscA family. (125 aa)    
Predicted Functional Partners:
NifU
Nitrogen fixation protein NifU; COG0822 NifU homolog involved in Fe-S cluster formation.
  
  
 0.779
kgd
Alpha-ketoglutarate decarboxylase; COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes.
  
   
 0.760
IscS
COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.
 
  
 0.732
RAM_11140
Hypothetical protein.
       0.662
RAM_46265
Glycine cleavage T protein; COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family.
 
 
 0.657
hemE
uroporphyrinogen-III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
   
 0.579
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
   
 0.573
RAM_19255
Thioredoxin-like protein.
  
 
 0.563
RAM_19315
COG0694 Thioredoxin-like proteins and domains.
  
 
 0.563
SufC
COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component.
  
 
 0.561
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.