| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Nei-2 | RAM_11310 | RAM_34945 | RAM_11310 | Endonuclease VIII; COG0266 Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. | COG0501 Zn-dependent protease with chaperone function. | 0.424 |
| RAM_01420 | RAM_11310 | RAM_01420 | RAM_11310 | TPR repeat-containing protein; COG0790 FOG: TPR repeat, SEL1 subfamily. | COG0501 Zn-dependent protease with chaperone function. | 0.449 |
| RAM_11305 | RAM_11310 | RAM_11305 | RAM_11310 | Hypothetical protein. | COG0501 Zn-dependent protease with chaperone function. | 0.631 |
| RAM_11305 | RAM_47470 | RAM_11305 | RAM_47470 | Hypothetical protein. | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | 0.692 |
| RAM_11305 | RAM_47760 | RAM_11305 | RAM_47760 | Hypothetical protein. | Hypothetical protein. | 0.459 |
| RAM_11310 | Nei-2 | RAM_11310 | RAM_34945 | COG0501 Zn-dependent protease with chaperone function. | Endonuclease VIII; COG0266 Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. | 0.424 |
| RAM_11310 | RAM_01420 | RAM_11310 | RAM_01420 | COG0501 Zn-dependent protease with chaperone function. | TPR repeat-containing protein; COG0790 FOG: TPR repeat, SEL1 subfamily. | 0.449 |
| RAM_11310 | RAM_11305 | RAM_11310 | RAM_11305 | COG0501 Zn-dependent protease with chaperone function. | Hypothetical protein. | 0.631 |
| RAM_11310 | RAM_27170 | RAM_11310 | RAM_27170 | COG0501 Zn-dependent protease with chaperone function. | Peptidase M41; COG0465 ATP-dependent Zn proteases. | 0.602 |
| RAM_11310 | RAM_29545 | RAM_11310 | RAM_29545 | COG0501 Zn-dependent protease with chaperone function. | LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. | 0.448 |
| RAM_11310 | RAM_47470 | RAM_11310 | RAM_47470 | COG0501 Zn-dependent protease with chaperone function. | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | 0.400 |
| RAM_11310 | RAM_47760 | RAM_11310 | RAM_47760 | COG0501 Zn-dependent protease with chaperone function. | Hypothetical protein. | 0.450 |
| RAM_11310 | ftsH | RAM_11310 | RAM_44885 | COG0501 Zn-dependent protease with chaperone function. | Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.602 |
| RAM_11310 | grpE | RAM_11310 | RAM_47005 | COG0501 Zn-dependent protease with chaperone function. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.400 |
| RAM_27170 | RAM_11310 | RAM_27170 | RAM_11310 | Peptidase M41; COG0465 ATP-dependent Zn proteases. | COG0501 Zn-dependent protease with chaperone function. | 0.602 |
| RAM_27170 | RAM_47470 | RAM_27170 | RAM_47470 | Peptidase M41; COG0465 ATP-dependent Zn proteases. | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | 0.460 |
| RAM_27170 | grpE | RAM_27170 | RAM_47005 | Peptidase M41; COG0465 ATP-dependent Zn proteases. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.460 |
| RAM_29545 | RAM_11310 | RAM_29545 | RAM_11310 | LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. | COG0501 Zn-dependent protease with chaperone function. | 0.448 |
| RAM_47470 | RAM_11305 | RAM_47470 | RAM_11305 | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | Hypothetical protein. | 0.692 |
| RAM_47470 | RAM_11310 | RAM_47470 | RAM_11310 | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | COG0501 Zn-dependent protease with chaperone function. | 0.400 |
