STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (336 aa)    
Predicted Functional Partners:
NadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
 
 0.999
NadC
COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
 
 
 0.999
RAM_11320
NUDIX hydrolase; COG1051 ADP-ribose pyrophosphatase.
 
   
 0.815
PnuC
COG3201 Nicotinamide mononucleotide transporter.
  
  
 0.811
RAM_36280
COG1985 Pyrimidine reductase, riboflavin biosynthesis.
  
  
 0.762
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
    0.749
nadE
NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.708
RAM_23390
NUDIX hydrolase; COG1051 ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family.
 
  
 0.699
RAM_42030
NUDIX hydrolase; COG1051 ADP-ribose pyrophosphatase.
 
  
 0.698
ComE
Competence protein ComEC; COG0658 Predicted membrane metal-binding protein.
     
 0.668
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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