STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (336 aa)    
Predicted Functional Partners:
NadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
 
 0.999
NadC
COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
 
 
 0.999
RAM_11320
NUDIX hydrolase; COG1051 ADP-ribose pyrophosphatase.
 
   
 0.817
PnuC
COG3201 Nicotinamide mononucleotide transporter.
  
  
 0.779
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
 0.768
RAM_36280
COG1985 Pyrimidine reductase, riboflavin biosynthesis.
  
  
 0.728
hisB
COG0131 Imidazoleglycerol-phosphate dehydratase.
     
 0.682
RAM_23390
NUDIX hydrolase; COG1051 ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family.
 
  
 0.682
RAM_42030
NUDIX hydrolase; COG1051 ADP-ribose pyrophosphatase.
 
  
 0.681
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
  
 0.676
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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