STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_11600Hypothetical protein. (312 aa)    
Predicted Functional Partners:
MsrA
Peptide-methionine (R)-S-oxide reductase; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase.
   
 
 0.728
msrA
Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 
 0.723
RAM_02545
Cytochrome C biogenesis protein; COG0526 Thiol-disulfide isomerase and thioredoxins.
  
 
 0.718
RAM_45300
Redoxin; COG0526 Thiol-disulfide isomerase and thioredoxins.
  
 
 0.718
RAM_46215
Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins.
  
 
 0.718
RAM_47200
NHL repeat-containing protein; COG0526 Thiol-disulfide isomerase and thioredoxins.
  
 
 0.718
RAM_11590
Pyridoxamine 5'-phosphate oxidase.
       0.532
RAM_11595
COG3554 Uncharacterized protein conserved in bacteria.
       0.532
rsfS
Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
    0.412
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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