STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_11615Hydrolase; COG4247 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase). (390 aa)    
Predicted Functional Partners:
RAM_47845
COG4222 Uncharacterized protein conserved in bacteria.
 
   
 0.915
GlpQ-2
COG0584 Glycerophosphoryl diester phosphodiesterase.
   
 0.612
RAM_11605
Hypothetical protein.
       0.584
RAM_11610
ECF subfamily RNA polymerase sigma-24 factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.
       0.584
hisF
Cyclase HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
       0.545
RAM_11625
Hypothetical protein.
       0.545
hisI
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
       0.545
RAM_11635
COG3759 Predicted membrane protein.
       0.545
RAM_39570
Large ATP-binding protein; COG5635 Predicted NTPase (NACHT family).
  
     0.544
RAM_20955
Large ATP-binding protein; COG5635 Predicted NTPase (NACHT family).
  
     0.525
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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