STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_11830COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (363 aa)    
Predicted Functional Partners:
CrtB
COG1562 Phytoene/squalene synthetase.
  
 0.986
UppS
Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.980
idi
Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
 
 
 0.979
UppS-2
Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.971
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
  
 
 0.956
CrtB-2
COG1562 Phytoene/squalene synthetase.
  
 0.941
RAM_02755
Trans-hexaprenyltranstransferase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
  
0.927
RAM_20770
Polyprenyl synthetase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
  
 
0.914
RAM_07705
Dimethylallyltranstransferase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
  
0.913
CrtI
COG1233 Phytoene dehydrogenase and related proteins.
  
  
 0.892
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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