STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FruRCOG1349 Transcriptional regulators of sugar metabolism. (262 aa)    
Predicted Functional Partners:
FruA
PTS system, fructose-specific IIBC component; COG1445 Phosphotransferase system fructose-specific component IIB.
 
  
 0.813
FruK
1-phosphofructokinase; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.
 
  
 0.801
PdxA
4-hydroxythreonine-4-phosphate dehydrogenase; COG1995 Pyridoxal phosphate biosynthesis protein; Belongs to the PdxA family.
  
    0.791
RAM_11900
COG0477 Permeases of the major facilitator superfamily.
     
 0.781
Lhr
ATP-dependent DNA helicase; COG1201 Lhr-like helicases.
       0.773
LacC
Tagatose 6-phosphate kinase; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB).
 
  
 0.769
FruK-2
1-phosphofructokinase; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB).
 
  
 0.594
FruB
PTS system, fructose-specific IIA component; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).
 
  
 0.555
GlpA-3
FAD dependent oxidoreductase; COG0578 Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.479
GlpA-2
COG0578 Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.458
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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