STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SdhB-2COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. (250 aa)    
Predicted Functional Partners:
sdhA-2
COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
 
 0.997
SdhC
COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.
  
 0.995
SdhD
COG2142 Succinate dehydrogenase, hydrophobic anchor subunit.
  
 0.992
NuoF-2
COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit.
  
 
 0.990
sdhA
COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
 
 0.985
SdhC-2
Succinate dehydrogenase cytochrome b-556 subunit.
  
 0.984
sdhA-3
COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
  
 0.979
RAM_11960
Hypothetical protein.
 
 
 
 0.960
kgd
Alpha-ketoglutarate decarboxylase; COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes.
  
 
 0.956
RAM_13045
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.930
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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