STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_12145COG0477 Permeases of the major facilitator superfamily. (417 aa)    
Predicted Functional Partners:
RAM_12150
COG1522 Transcriptional regulators.
 
     0.846
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner.
  
    0.773
RAM_24290
COG0477 Permeases of the major facilitator superfamily.
  
     0.695
RAM_25075
COG0477 Permeases of the major facilitator superfamily.
  
     0.594
RAM_35890
Hypothetical protein; COG0477 Permeases of the major facilitator superfamily.
  
     0.590
hflX
GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
  
    0.520
RAM_46690
COG0477 Permeases of the major facilitator superfamily.
  
     0.495
RAM_16910
Hypothetical protein; COG0477 Permeases of the major facilitator superfamily.
  
     0.467
RAM_31305
COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases.
  
    0.441
RAM_21280
COG3860 Uncharacterized protein conserved in bacteria.
 
     0.415
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.