STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GalKCOG0153 Galactokinase; Belongs to the GHMP kinase family. GalK subfamily. (394 aa)    
Predicted Functional Partners:
GalT
COG1085 Galactose-1-phosphate uridylyltransferase.
 0.999
GalM
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
 0.987
GalM-2
Aldose 1-epimerase; COG2017 Galactose mutarotase and related enzymes.
  
 0.980
GalE-3
COG1087 UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
 
 
 0.973
TroR
COG1321 Mn-dependent transcriptional regulator.
       0.880
GalE-6
UDP-glucose 4-epimerase; COG0451 Nucleoside-diphosphate-sugar epimerases.
  
 
 0.848
rpsL
30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
      
 0.765
LacZ-5
COG3250 Beta-galactosidase/beta-glucuronidase.
 
  
 0.749
GalU
UTP--glucose-1-phosphate uridylyltransferase; COG1210 UDP-glucose pyrophosphorylase.
     
 0.739
LacZ-3
COG3250 Beta-galactosidase/beta-glucuronidase; Belongs to the glycosyl hydrolase 2 family.
 
  
 0.736
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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