STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Experiments
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[Homology]
Score
RAM_12305acetyl-CoA synthetase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (893 aa)    
Predicted Functional Partners:
AcuC
Acetoin utilization protein AcuC; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.
 
    0.942
nnrD
Ribokinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NA [...]
 
    0.603
KorA
COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit.
  
 
 0.592
RAM_18760
Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
  
 0.557
RAM_18765
Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
  
 0.557
RAM_27510
COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
  
 0.557
RAM_12310
COG1680 Beta-lactamase class C and other penicillin binding proteins.
       0.550
RAM_11230
COG1522 Transcriptional regulators.
 
     0.524
SseA
Rhodanese-like protein; COG2897 Rhodanese-related sulfurtransferase.
       0.496
RAM_30055
COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits.
 
 
 
 0.480
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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