STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ArsACOG0003 Oxyanion-translocating ATPase. (377 aa)    
Predicted Functional Partners:
RAM_12460
Hypothetical protein.
  
    0.867
RAM_12450
Cyclase/dehydrase.
  
    0.861
Glk
Glucokinase; COG1940 Transcriptional regulator/sugar kinase.
       0.837
RAM_12445
Metallophosphoesterase; COG2129 Predicted phosphoesterases, related to the Icc protein.
 
     0.827
RAM_12440
Hypothetical protein.
  
    0.766
PyrF
COG0284 Orotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
 
 
 0.714
FadD-3
COG1022 Long-chain acyl-CoA synthetases (AMP-forming).
  
    0.535
RAM_45410
COG0003 Oxyanion-translocating ATPase.
 
     0.500
ileS
isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
  
 
 
 0.459
RAM_39630
Mov34/MPN/PAD-1 family protein; COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily.
   
   0.452
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.