STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_12785Riboflavin kinase/FAD synthetase; COG0196 FAD synthase. (150 aa)    
Predicted Functional Partners:
RibE
COG0307 Riboflavin synthase alpha chain.
  
 
 0.925
RAM_32420
Riboflavin kinase; COG0196 FAD synthase; Belongs to the ribF family.
  
  
 
0.917
RAM_06600
FMN reductase; COG0431 Predicted flavoprotein.
    
 0.907
RAM_45520
FMN reductase; COG0431 Predicted flavoprotein.
    
 0.907
ribH
Riboflavin synthase beta chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
  
 0.845
RAM_36280
COG1985 Pyrimidine reductase, riboflavin biosynthesis.
  
  
 0.698
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
  
 0.652
RAM_12810
3-ketosteroid-delta-1-dehydrogenase; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
     
 0.633
RAM_12790
COG2030 Acyl dehydratase.
       0.628
RAM_12795
Oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.
       0.619
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.