STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MhpC-22-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). (281 aa)    
Predicted Functional Partners:
RAM_12830
3,4-DHSA dioxygenase; COG0346 Lactoylglutathione lyase and related lyases.
 
 
 0.994
RAM_12820
COG1960 Acyl-CoA dehydrogenases.
 
   0.942
RAM_17220
COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
 
  0.925
RAM_36905
COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
  
  
 
0.908
RAM_12815
Hypothetical protein; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
 
     0.873
RAM_12805
Rieske (2Fe-2S) domain-containing protein; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.
 
 
 
 0.868
RAM_12835
Flavin reductase domain-containing protein; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.
 
    0.844
RAM_12810
3-ketosteroid-delta-1-dehydrogenase; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
 
   
 0.812
RAM_12800
Hypothetical protein.
 
     0.796
RAM_34475
COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
  
     0.674
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.